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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d835d788ab3591d2043082282e896c5e1709af0a5eedf8e613cba171a647a85' 
  AND token = 'PZog+mC1L9uRMLkiBAeMy2rpTnJgOedq7JnB5lttgP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}