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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e7efb5d01579768ee42cb15b7ad224d7d87b7daf3253eb3af43611fe6a4e3e' 
  AND token = 'jkhqvtKl9gxxhABD7FL9k8UapBFIzCMtuf2m0MkSff8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}