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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f1a606c8c03dd77c4e7510fdebfabb9d1e135ca50e3c4470c8ea285d942fece' 
  AND token = '0js/vCrl9oN/tdZqGaJ06JZddMFPd9fDTm+x9PqC7Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}