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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2fe3160d3d277a5014aa63e1549e46589fc9d8c7f7cdd61e9beb30e048ac404' 
  AND token = 'iJ1+T2eLLb3MdvgFvFSGTEM2P49V0QXR+rAD68311pY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}