SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68ed6729c6cbe61be8ba337e104981c7fbbbb249909d9e67248250b5e41da58c' 
  AND token = '95UoKjT5TeXv10gQ1QkSAgX/1enV5C9AAyG4dfJ+iNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}