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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7501f8443f5b85adc7d2d8aa045f15ca14bb9aa1c981b1ba681bf24e91bdabd2' 
  AND token = 'NkhrGNPQ6q162aJqeLvEFWsD78AFytHYWSXQzwXPQzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}