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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ad2f97f860f7ec1940ea17a7e517cb427be17e4fb3681cae4b756f0c3b1b098' 
  AND token = 'w/oM8EenZ80G27mp2qaYz0V2y9kVEvOHhUvhwvGxaCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}