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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b48e2e5832c39dcf40ae55a03584ad9eef9eca28df8aea7efcebcdde071b100' 
  AND token = 'TlpXm8lDLXmHcT9eIk5aCGnYGE6Qnb6+itCr5NZTKCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}