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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9890d11ea0c3cf31733c23dccd02f34f62b7138c24b6900a914540ca3c72faf9' 
  AND token = '43jWttWUMa7EfhG+OE9AjEWC4olY2nQRqlFsW9fCFIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}