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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd5a1663eec0b4bee50e81b316cb1a1844e5960f45b498c72ca441c57c15a84' 
  AND token = 'YLdZx2MkRkCgLpks+XuRf+aLHfXCFqYcg5lKmtE6Y7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}