SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db0e5b3c0469a5d37b682c433704021b31e2b77349b221d842ab10a50727279f' 
  AND token = 'cHNUam/G/si4aaX9WgxHOhpW6cY0wcsOco4yH52VRNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}