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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35b5ce881929b1f51755020bf8cb7b3e8cb81aa455eb0b28e4635d9152485695' 
  AND token = 'G+cz3LYgR+1uCQSbNK4FPGnxyysiM1gbBatwyqVabjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}