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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49bf91195266d5eebb1914d66c16947774c3b026699a27bb80fa6d0af5f3cce3' 
  AND token = 'TsZpuNJ+JUqr7yJp7PKkD5vrkaTWUMkHUEfO0pdH1U4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}