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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd606df33bd2dcf2eb8348c3eed2f7ae4d8763a4b92fcb834f931e012a71e1127' 
  AND token = 'Vf/1fdavzR5xWjmeRhHN1agkArZiBNiBuekXYXUIK50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}