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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bde0ae9fbc634d1661d3c67747d9f8e006273a6091b1d5af4acbe6b645fc76d9' 
  AND token = 'zQhDtl4RTgFHdSX3ETKM6Es+OeQzOtpL0oqcn1cJyH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}