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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b220a1f020947ad6bd2be2254a1c7dd2cecc8b6a99f40895b1803ce67db518f' 
  AND token = 'AwylQ00IW0a9RzzY5CeA0cnBlIxqz9pyVn6CKJHpVPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}