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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c8498d53ee9773143e33842ddd6105fd5549b4bbaeaece22b47a449f177b620' 
  AND token = 'ML6ekrTXFprpJlyq0L6YQY6z13/IMX15+zqWc8jnqbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}