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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8d814f34d902a95b65374aa0b3d2f88359083ff03f17a363a91828df57103bb' 
  AND token = '/xDoFR2ogxPMR+vZ81fmL7+V8KXCPKK1Ed3LU1WlXM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}