SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cd63712500fd29437616b94988c8f6a98cade7dce8dfbe74d2bc45eea44c4dc' 
  AND token = 'zXA2hJh5hrEglrL7m3BM5DXy1YJEwGk4zRY6vEM9Zyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}