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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c761ccefc28361d3a6d708782c70423226bd046958c3824a29ac6979467adab' 
  AND token = 'TY8PN2QbdW0T+ImBOnDQY3eYaz0He1dUuIqin0ZkE+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}