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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e7121d9ebc7cd9eb570f38f8fe6efa3ebc89d794c9e320f50108319ebc07f5' 
  AND token = 'uOLZmM3cGPEGQ9kvu6hHmRUlH6zGUnhWnM1O65xwQ8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}