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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7049797011e5c01270e654c9bb08f7672cdc217ea63526b85f5fd102178e1ef' 
  AND token = 'HrF+NhQb9HuIBBf8JdAw1z+gtorPo6HIj4aGdq1mJAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}