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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1072d5f4427e5f42ff53b2b842ac772e7790b293cca221687a9a249c9ca8f9f' 
  AND token = 'Ju4ZYFxPZKNNi+f8/zn+JoW8ce+6ZcG1aMtLr4EOXPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}