SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b69c930730d59e022938ca1bf936963b9aaf346eb41d0c57abd040a65ec8b7e' 
  AND token = 'G5slT+Rg6tB4D5e1sMK5reYs8mNtcsVb4yDR9joOE4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}