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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea1a17ece1274c63a704ffd73f9e08808158c06b1e47ea490a859de721a5128a' 
  AND token = 'x05Gh9i1KZbF3habG3Tit08WrikRLnsZzx7GydDVKnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}