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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdef2a337e792621a167d269e57585c5220585aaf0d5f10a476e76640a8bc16c' 
  AND token = 'IrZo/9yVtfG3D0Id+M3EEEDIfXorfPAI2Hv+aYBusjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}