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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f7446a8d2b5c68debe7de36a5a93e8f085379bdaf12c0b63ac571bbec7c2436' 
  AND token = 'Fx+twxBvLO8YjGjy3kYyRbWmOsa0m4zvgHdVwxLb9bY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}