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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bae2cd3317cf0b2c0c28c1ea54d2a862fa37648a1ff178617f9f73f6845c50' 
  AND token = 'X4D0ueI4AkICgMQD5mjtuwxxCFT+9+MelPoKGvXfRp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}