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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '972d3dd56772c6c36f91e159327521dce20aa78b192dc84c35bac2f6fe82b59f' 
  AND token = 'UmMVaRth13cdvMvo3u3qbx0BrH5vsA6OQuWtMek9doo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}