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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6214a968ec70a12c7b0e714624b68a2f6751fe253ce33bcf5d02c26279fa910' 
  AND token = 'ViUZP+fLYs/W5ux8pwUN/AM+iQF2bzSgVesniRNiyUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}