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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8475aca830422eabe3e014a34ffeb18e54da125259fc4b159de658b24f9c7e10' 
  AND token = 'LUWftOb19j6codTXKj7p/Nw8uYJc4WJOdb5dhz7C72M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}