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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3adb035917226fe5484aeec59e48ac0e8816b505d202a036931064875639bbb' 
  AND token = '9nO0LyWyyCPGMxFdjN9FbuOHG/PIMNG6HqOPSGbkOAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}