SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ce00fc5232544a44251ba7d06ea20d5de81f9e0b99b2f03f276d25a6e130fe2' 
  AND token = 'jJGWDi4+dmUwvMEVEX8KaAyGi++ykxnWPC1iVKMBOjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}