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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96f34db08744bdefd7917a9a2f7bb3497fa99680782076b8678cc0ecfc3da2d2' 
  AND token = 'MYfuCKjs8p6Wdmelsg5ob25oCCUZLRTGATZbAE5GPyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}