SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25bd7262a61ecd4bc17af2414e4d08c8d3f76a93cebf45e823679606ddfbc117' 
  AND token = 'vuFw5D2GDDHMFwzbUxIpA/eruZb9HqKGPg6yKM/5/8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}