SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b65e0b5b5a805cac66ca175a3ec8d7b75e8fa1010ffb036fedc9aa0a5387835c' 
  AND token = 'BWby5dYeGMGwLiJ887wcM5LNTJ2LMgZ/MWv0d0ZZCUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}