SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3793cf20a8c5d8c37fffe1633edc3b004d79b7f0d1f9672eb16b735e54be2a39' 
  AND token = '9kyZkn6YKBc/tcNRAnRS2KRT1G1JafVPcnrlVxBkSHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}