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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3355d04800885060e84f5f05acc32b06ff33f2b1d6e59115033c4646f3cadf91' 
  AND token = 'ZmuafDlmSoE4bVXhC/ALSZRt7qTKtVeu9IaqHUTjpkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}