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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '607911d2b39369e65e71b4606b149d6df201aa208f117bf0775dbf072925402e' 
  AND token = 'U0ZgPE72uFSkg+T7eQxfoqFJoA261i9N/kEp+2Xa0sA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}