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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f86f35796ce86811140aa021b9d524ba2a25e35b028032256683390c8083ad92' 
  AND token = '4ns+XYYLr4BF7n4RoWUtCGMbdW4cz2lANzH9F8O1o8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}