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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff538fdcd70cdfd9f540d237dc1253bf3f9c42a81d255b8aa7763a103c5bd67' 
  AND token = '4HpKnoD6yZMac4Mo/wsMuWOBBvL4XVNcKgFntuwVcZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}