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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a80e762529062bc4a8069c6ffe31b7a2d7a68732c04dabfca9a7d8658c450a4' 
  AND token = 'xHOMOA2SfBaTmkjbB8DahuXdJ8aNe3nDBKWi91rjvXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}