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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd25d2e415822d6c3b7d66eafd5d268589a05ef941d8fd9cdf9cb54737229e421' 
  AND token = 'UiHSiHMmMfMIAfFBTmVxtTgDFwE2Xt+yJ3YWJ++5F/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}