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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7496e319692fde8f84bca152476fcab4ad36c44b1fe1280390997f39f7d0c123' 
  AND token = 'ZHkobMXmPaTMXH3myx6ZcqKBugw+ns4Pu3LPIjw01lc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}