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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e28af5d53d44807a0381e766b24c648dd4f69c61b82bb07202d76e7eacaba0' 
  AND token = 'XenFk8demM4o2qyBvg1CniZVch0DJzLNb8+ZlcC+3mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}