SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b84c94a2d829afb1d4dca4e932ede3b63fb1651ca911d299790be13fc420523' 
  AND token = '/bpU+An4I+f69bzdHbBtbpPZMxDkUr9c5tROJZn13Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}