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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9f8f732cc09d5cac012edb8eddccc03ecda10cc1cb376b95ad6dab88c17729f' 
  AND token = 'IuwCctvkzTZYqU8mPgUUnps7HDC/wCHiLwlVu0Q4AUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}