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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddbebd3c55b48fa7cb97348487ad15946cada7ca98bfeda4fb7448f1ebc123c9' 
  AND token = '/HqrnFt/da+c6M7e//MSkoZJWx2FfSML9MSx0gic9Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}