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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d93e8f5101be6ca0582eee394a7be60fc2b2d027e278a87777ee78997157b18' 
  AND token = '4N4I/3jLCLX5ubMhtYyYjLVywuQKocW5xdSnzn8UkCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}