SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c28531fa4cbd4e35cf17e5ff505762a3fa36f05a85390abdcb592ace20812838' 
  AND token = 'bIDVscfiqPs6aDl0nH9gQVlMXbpnJ4EijVuYbpqQl4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}